SVF (Stromal Vascular Fraction)

SVF is separating stem cells from fat whereas.SVF consists of 40% of Stem Cells and Growth Factor. They are highly effectivefor repairing cells and degenerate body parts.

SVF stands for Stromal Vascular Fraction, i.e.,a method for separating stem cells from fat.

SVF has been discovered and developed from 2001by a scientist who used liposuction and decomposition to separate element withno fat cell called Stromal.

When comparing with bridge construction,Stromal can be compared as a bridge part with curved steel or cement whereasvascular is blood vessel and Fraction is element.

Therefore, Stromal Vascular Fraction is afraction obtained from liposuction and separation of fat tissues to gainStromal Vascular Fraction.

Why does it play the roles in many treatmentseven injury or osteoarthritis? This is because there are many elements inStromal Vascular Fraction and.

Important elements in SVF are

1. Adipose stem cells 2. Mesenchymal stem cells 3. Progenitor cells 4. Growth Factors

Stem Cells can be transformed to any kind ofcell in our body. Among stem cell groups, we found that they play the roles inrepairing, enhancing, and healing injured areas, wounds, or inflammation morerapidly.

Why? This is because inflammation process isorderly occurred through stage 1, 2, 3, and 4. Stem cells will reduce thoseprocedures of inflammation therefore the duration of inflammation will beshortened leading to more rapid recovery. Consequently, all connective tissueswill be reduced and tissue cells will be repaired to be normal without leavingany scar.

There are many people who are confusing betweenSVF (Stromal Vascular Fraction) and other kinds of treatment, for example, PRP(Platelet Rich Plasma). However, SVF is currently utilized in healing hair lossand thinning hair and it is found to be highly effective.

What are difference between PRP andSVF?

The purposes of use of both SVF and PRP arecompletely similar. But the important feature required is messenger that will controlcell functions we need.

PRP (Platelet Rich Plasma) contains a format ofmessenger with a kind of Growth Factor whereas SVF (Stromal Vascular Fraction)contains another format of messenger obtained from cells that are its elements.We also found that SVF will release a large amount of growth factors with sometypes of growth factors that may not be found in PRP. Therefore, somescientists found that utilization of SVF to treat hair loss can give bettertreatment results.

Methods to seperate SVF from Fat 1. Use enzymes to digest obtained fat. 2. Use automatic machine such asbody-jet with Q-graft, etc. to suck fat and separate SVF in closed system.

However, it was found that digestion withenzymes will yield larger amount of growth factors or required cells based oneach patient. However, the process of digestion with enzymes is morecomplicated whereas automatic machine may be more expensive but its process isless difficult. However, automatic machine may give smaller amount of cells,stem cells, or growth factors. There is also a problem on U.S. laws or FDAregarding digestion with enzymes, i.e., whenever enzymes are used in cell orstem cell transformation process, it will be deemed as Manipulated Cell.

บทความโดย นพ.ธิติวัฒน์ วีรโรจน์รัชกุล https://journalofprolotherapy.com/understanding-adipose-derived-stromal-vascular-fraction-ad-svf-cell-biology/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506773/ https://pubmed.ncbi.nlm.nih.gov/29554209/ https://pubmed.ncbi.nlm.nih.gov/31541565/ https://jcadonline.com/stromal-vascular-fraction-alopecia/